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How effective is in vitro fertilization, and how can it be improved?
Objective: To measure IVF effectiveness, which is defined as the cumulative incidence of live delivery over real time in women after commencing IVF treatment.
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Design: Population-based retrospective cohort study.
Setting: IVF clinics in Western Australia (WA).
Patient(s): All women ages 20-44 years inclusive at start of treatment, commencing IVF in 1982-1992 and 1993-2002 at clinics in WA (n = 8,275).
Intervention(s): Data on IVF cycles were extracted from hospital records and a statutory reproductive technology register and linked to records of births.
Success rate of ivf by ageMain outcome measure(s): Cumulative incidence of an IVF-attributed live delivery and cumulative incidence of an IVF-attributed or IVF treatment-independent live delivery.
Result(s): IVF effectiveness in the 1993-2002 cohort was 47% overall.
It was highest in women ages 20-29 years at the start of treatment, measuring 58%; and 79% with the inclusion of IVF treatment-independent deliveries, and declined to 22% and 33%, respe
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