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  • When platelet transfusion is required
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    Is blood group matching necessary for platelet transfusion

  • Platelet transfusion in dengue
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  • Platelet transfusion guidelines
  • INTRODUCTION

    Hemostasis depends on an adequate number of functional platelets, together with an intact coagulation (clotting factor) system. This topic covers the logistics of platelet use and the indications for platelet transfusion in adults.

    The approach to the bleeding patient, refractoriness to platelet transfusion, and platelet transfusion in neonates are discussed separately.

    ●Evaluation of bleeding – (See "Approach to the adult with a suspected bleeding disorder".)

    ●Refractoriness to platelet transfusion – (See "Refractoriness to platelet transfusion".)

    ●Neonates – (See "Neonatal thrombocytopenia: Clinical manifestations, evaluation, and management", section on 'Platelet transfusion'.)

    COLLECTION METHODS

    There are two ways that platelets can be collected: by isolating and pooling platelets from units of donated whole blood or by collecting platelets via apheresis directly from a donor.

    Most platelets in the United States are collected by apheresis.

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